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Comparison of Pregabalin with Pramipexole for Restless Legs Syndrome NEJM 370:621-631,667, Allen, R.P.,et al, 2014 See this aricle in Pubmed Article Abstract Pregabalin provided significantly improved treatment outcomes as compared with placebo, and augmentation rates were significantly lower with pregabalin than with 0.5 mg of pramipexole..

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